how can configure X52 to be used with the PMDG 747/737s i.e dissconnect autopilot.....etcis there any possibilty that reverse thrust be configered for the throttleThanks

If you go here http://www.saitekusa.com/usa/down/x52pro.htm ,you can download the Saitek profile, for all FS versions to go with the Saitek stick. You can configure your stick to your liking. Remember you can also adjust some settings in your FSUIPC. Now if that will work with PMDG, i guess so, Im not using the X52, maybe if it doesn't, make a post over at their forum.