PMDG 777 Random throttle inputs, random failures with no service failures enabled, now won't uninstall?

PMDG 777 tech reps;

I'm having a series of problems.  Even after a fresh FSX reinstall, PMDG 777 install, eventually the aircraft acts strange.  All other aircraft act normal.  For the longest time PMDG 777 with all service packs worked correctly.  Here are the problems;

1.)  At random my throttles will advance or engine rpms will advance to full 100% on their own but not isolated only to PMDG 777.  wondering if there is a fix for that or a bug in FSX.

2.)  Main issue:  Recently after I just did a fresh FSX reinstall and reinstalled all my aircraft including PMDG 777.  Now after about an hour or more into the flight on Auto pilot, the aircraft will start to fly off course with autopilot still engaged.  Then random failures will appear.  If I go to disengage autopilot, the aircraft is completely out of control and tumbles in the air.  All hydraulic, engine, systems go off line.  Never used to do this if I disengaged autopilot in cruise.  All service failures are off (not selected in CDU), FSX failures are all disabled.  There should be no failures of any kind.

3.  Uninstalled PMDG 777, reinstalled and still have the same issues.  This time I uninstalled and deleted all associated files.  Ran CC cleaner to clean out the registry.  Reinstalled, still get the same problems.  Now I try to uninstall the 777 from the control panel and I get this message that pops up after trying to uninstall;

"An error (-5005 : 0x800700020 has occurred while running the setup.

Please make sure you have finished any previous setup and closed other applications. 

If the error still occurs, please contact your vendor: PMDG Simulations, LLC.

(##ID_STRING1##)."

Why can I not uninstall the 777 now??  Thanks,