Hot keys on keyboard and joystick stopped working

Good evening,

I’m not sure what the issue is... but some of the keys on both my joystick and keyboard aren’t working.. like “b” for altimeter, “h” for set heading indicator... can’t even decrease or increase flaps on my joystick.. brakes don’t work sometimes.  I’ve tried closing other windows, dragging windows around etc, no dice.  It makes it hard to enjoy this.  Any help would be immensely grateful.

thanks!