I boot Flight Simulator with the CD in the E: drive, but it has broken and no way to start if I put the CD in the other drive (F:).Could you help me ?

Hi Auvergnat, did you sort it out meanwhile? I'm not good at this, but there might be an entry in the OS's registry causing this (i.e. changed drive letters)? What happens if you swap the drives (you might need to change the master/slave jumpers)? Please be more specific if you require further help. Welcome to this forum, btw. Good luck and kind regards Jaap