I have acquired 15cm/pixel imagery all in DDS tiles measuring 2048x2048 . In total 195 tiles . I'm pretty new to photo scenery and I was just wondering is there a way this can be used in SBuilderX and how ?

If the imagery has some GIS data that comes with it, Lat and Lon, you can manually add the file(s) into SBX. I don't think you will be able to add all at one time, so it might require a couple, three separate projects due to memory constraints.