Crash on start help pls

I am starting the 737ngx and it loads the cockpit which appears all grey showing no controls, and then it crashes! any advice would be appreciated. Wayne. Problem signature: Problem Event Name: APPCRASH Application Name: fsx.exe Application Version: 10.0.61637.0 Application Timestamp: 46fadb14 Fault Module Name: PMDG_737NGX.DLL Fault Module Version: 1.0.0.0 Fault Module Timestamp: 4e4a3aef Exception Code: c0000005 Exception Offset: 0012375f OS Version: 6.1.7601.2.1.0.256.48 Locale ID: 3081 Additional information about the problem: LCID: 3081