Hello friends, really stuck with the above problem which continues: could not load file or assembly 'Microsoft.FlightSimulator.SimConnect, Version=10.0.61259.0, Culture=neutral, PublicKeyToken=31bf3856ad364e35' or one of its dependencies. The System cannot find the file specified. Using Windows 10, P3D v. 2.5, 12 GB Ram, Asus PT6D Motherboard. This worked fine until I deleted some old FSX files about a month ago. Not sure if the "redist" file is corrupt in P3Dv2. Is this an Addon problem? I don't have the computer background to figure it out...please help if you are able.

Thanks, J. Preston

try reinstalling SimConnect it solved my Problem there :)