It works with Navigraph SimLink running on the primary computer (system running MSFS 2020) and Navigraph Charts on a separate computer then selecting "Enable moving maps". One thing I have noticed is that after I end a flight SimLink reports that it has "[old data]" in red for subsequent flights I had to restart SimLink.
I have this setup with one variation and it works fine. I had an old Saitek yoke so I took the control board out cutting off all wires to the yoke pots and switches. I placed the control board into a box and wired on a short USB plug (messy but it works). Now I just plug the throttle into the board so I'm not tripping over a yoke. MSFS2020 recognizes both the yoke and throttle controls but everything on the Alpha control and throttle work just fine. The next time I fly I'll remove disable/remove the Saitek yoke controls and key mapping just to prevent any issues.
Stephan:
Thank you for the information on the updated simlink as it is working perfectly on my primary computer, the one running MSFS 2020. Is there a setting or configuration change I can make to have simlink and charts run on my secondary PC?