I updated today following the instructions from P3D website. I'm extremely impressed with load times now. Load time out of (Fly Tampa) Sydney, Australia, was 60 seconds in PMDG 747-8, with ORBX (Vector, Trees, & Australia), FS Global Ultimate, and ASN + ASCA.
Process Explorer reported 99GB VAS usage on load.
I'm loading off a Samsung 1TB NVMe PCIe SSD and load times on v4.4 were around 5-6 minutes and it was doing my head in - I could go downstairs and make a cup of tea at 6%, come back and it still hadn't loaded.
I've also updated ASN and ASCA, and all seems to be working well atm.
In a nutshell, v4.5 has cut my load times by around 80%, breezing past 6% like it was any other number.