Mouseover issue

Not sure if something in the last update caused this, but usually you get 3-4 seconds after you mouseover a switch, button, etc to make the actual selection. But 3-4 times during the flight, when I need to use the mouse, the mouseover cuts out almost immediately and I cant select anything. It's a USB mouse. I've done all the usual stuff(unplug/plug mouse, reboot computer, made sure I'm in Legacy mode). Hope I've properly described the issue and thanks for the replies in advance.