SS Ohio

They did use dog sleds. There were plans to try and use a plane, but it was decided to go with the dogs for the first batch of serum. For the second batch they tried to use a plane, but they couldn't get it to start.

I am only about half way through this flight myself, but so far it has been quite a challenge. I decided to recreate the 1925 serum run to Nome. I took off from Nenana at 04:00 on January 28, 1925 (the serum actually arrived at 21:00 on the 27th, but I didn’t want to fly the whole trip at night). From there, follow the Tanana river until it merges with the Yukon, then follow the Yukon all the way down to Kaltag. Then fly SW through the Mountains until you hit the coast near the town of Unalakleet, turn north and follow the cost up to Norton bay. Cut across the bay and then follow the cost to Nome. Total trip should be something like 550nm. I am doing all this in stormy weather in the Stearman, so I have to follow the terrain closely or I will get lost very easily.