Saitek has posted this on their Facebook:

 

https://www.facebook.com/SaitekProFlight/posts/1191403077552878

 

If you can't see it for some reason:

 

"We at Saitek are acutely aware of the current issues of some flight-sim hardware with Windows 10. We are working on solutions and will post updated drivers at the very earliest opportunity. We expect these updates to be complete by the 11th of September. We sincerely apologize to customers affected by this and value your continued support."

Beta version is available for download:

 

 http://madcatz.kayako.com/Knowledgebase/Article/View/604/46/windows-10--saitek-hotas-beta-drivers-and-software-release

 

Read the installation instructions, as you might not want to try this version.