I've been simming since FS2000 and I'm currently 19 y/o. Didnt have flying experience other than some turns, and cruising on a 150 long time ago, however I took an introductory flight in a Cessna 172 on july and I may tell you that the instructor thought that I had already some sort of training! I truly went from Cold and Dark to Cold and Dark all by myself with him just sitting there.
It was way easier than the Sim as I didnt have to click everything with my mouse or use this joistick.
Now, the 737 is a bigger deal. I'm self confident that I can take over it in case of an emergency and land.
Maybe not a good landing, but definitely I could land it. As someone said in this thread, is just a matter of 10-20 mins till you get used to the aircraft feel and the fear goes off :-)
Just my .02c