Ok, after about 6 months of sitting on the sidelines and taking a break from simming, 2.2 has me convinced to give it a try. Can anyone recommend some good NI settings to start with?  I've got a 3770k at 4.7ghz and a GTX 680 4GB.  Thanks!

In 2.1 I got better results without NI. Try it first, not sure how effective NI is in 2.2 or if you indeed will need it.

 

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I find NI to be for when you want to sacrifice a bit of fps for some better visuals through AA. If you're not happy with the default anti aliasing then tweak NI but otherwise I'd just leave it alone if you can handle any shimmering or jaggies.