In order to turn off game mode just press the windows key+g while in the game.
 

11 hours ago, sultanofswing said:

In order to turn off game mode just press the windows key+g while in the game.
 

But this isnt working on my system 

Thanks Michael Moe 

On 18/10/2017 at 11:24 PM, bills511 said:

I didn't know P3D was a game. So I don't use game mode.

It's based on fsx.  It's a game

14 hours ago, Michael Moe said:

But this isnt working on my system 

Thanks Michael Moe 

Maybe you have it disabled or you need to configure the keys to activate it.