I was using both with v4.5 for a long time. I installed v5 late last evening and simply started v5 to set it up last night At that time ChasePlane started and indicated that v5 was not supported. As I was also waiting for FSUIPC 6 to be installed I closed the sim. This morning when I started v5 everything worked from the start. I always start TrackIR before starting the sim, as I do with Active Sky and Skyforce, and then ChasePlane is started by/with the sim. I have both v4.5 and v5 installed on the same SSD.