I updated my system from 7 to 10 about a week ago.
Took a while to get things running but everything I had working before runs like a charm.
FSX Steam, EZCA, PMDG NGX & 777, RAAS, REX + Soft Clouds, ASN, VAFS5, Air Traffic Manager and WoAI.
If you find a roadblock just google. Every thing you need to get it up and running was already described by some clever lad.
Zero issues for me.